- A Case of Methimazole-induced Pancytopenia: Successful Treatment with Recombinant Human Granulocyte Colony-stimulating Factor.
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Joo Hyoung Lee, Jihyun Lee, Sang Hun Sung, Sung Hwa Bae, Sang Gyung Kim, Hoon Kyu Oh
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J Korean Endocr Soc. 2006;21(6):548-551. Published online December 1, 2006
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DOI: https://doi.org/10.3803/jkes.2006.21.6.548
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- Methimazole has remained the cornerstone for the treatment of hyperthyroidism since 1940's and it is a well-tolerated antithyroid drug. Pancytopenia is one of the major side effects of methimazole, but its occurrence is very rare. There have been some case reports about methimazole-induced pancytopenia that was treated with recombinant human granulocyte colony-stimulating factor (G-CSF), but its usefulness is still controversial. We present here a case of a 50-year-old female who had been treated with methimazole for hyperthyroidism and she subsequently presented pancytopenia. G-CSF was given for 10 days and she successfully recovered from the pancytopenia.
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Citations
Citations to this article as recorded by  - A Case of Graves' Disease with Pancytopenia
Jong Ho Shin, Hyun Jin Kim, Si Bum Kim, Dong Pil Kim, Bong Suk Ko, Dong Soon Kim, Ji Myung Kim, Soo Jung Gong, Jung-Ae Lee
Journal of Korean Endocrine Society.2009; 24(4): 272. CrossRef
- A Case of Fetal Alcohol Syndrome with Secondary Amenorrhea.
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Yoon Young Cho, Hyo Jin Oh, Seok Jae Han, Sang Hun Sung, Gyu Hwan Bae, Ho Sang Shon, Hyun Dae Yoon
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J Korean Endocr Soc. 2005;20(5):524-530. Published online October 1, 2005
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DOI: https://doi.org/10.3803/jkes.2005.20.5.524
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1,733
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- Alcohol ingestion during pregnancy can be damaging to embryonic and fetal development. A specific pattern of malformation, identified as Fetal alcohol syndrome, has been documented in 1~2 of every 1,000 live infant births Fetal alcohol syndrome is characterized by growth deficiency, facial abnormalities, cardiac defects, minor joint and limb abnormalities, as well as central nervous system dysfunction, including microcephaly, mental retardation and abnormal neurobehavioral development. However, there are few reports of fetal alcohol syndrome associated with hormonal abnormality or amenorrhea. Recently, a case of secondary amenorrhea, which developed in a 19-year-old woman with fetal alcohol syndrome, was experienced at our institute, but the exact cause of the amenorrhea was difficulty to find. Herein, this case is reported, with a review of the literature.
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Citations
Citations to this article as recorded by - Alcohol Use during Pregnancy and Related Risk Factors in Korea
So Hee Lee, Seung Ju Shin, Seong-Du Won, Eun-Ju Kim, Dong-Yul Oh
Psychiatry Investigation.2010; 7(2): 86. CrossRef
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